A Time to Event Tutorial for Pharmacometricians

A Time to Event Tutorial for Pharmacometricians

Algebraicmethods for Discrete Event Systems - a Tutorial

Discrete event dynamic systems (DEDS) are treated in a mathematical framework using algebra and polynomials over finite fields. In this framework DEDS interacts with the environment by signals rather than events. The polynomial framework give symbolic representation of a DEDS behavior and canbe used formodeling, synthesis and verification. Two tools, Gröbner basis and binary decision diagrams, ...

a new approach to credibility premium for zero-inflated poisson models for panel data

هدف اصلی از این تحقیق به دست آوردن و مقایسه حق بیمه باورمندی در مدل های شمارشی گزارش نشده برای داده های طولی می باشد. در این تحقیق حق بیمه های پبش گویی بر اساس توابع ضرر مربع خطا و نمایی محاسبه شده و با هم مقایسه می شود. تمایل به گرفتن پاداش و جایزه یکی از دلایل مهم برای گزارش ندادن تصادفات می باشد و افراد برای استفاده از تخفیف اغلب از گزارش تصادفات با هزینه پائین خودداری می کنند، در این تحقیق ...

Tutorial: Formal Methods for Event Processing

Organisations require techniques for automated transformation of the Big Data they collect into operational knowledge. This requirement may be addressed by employing event processing systems that detect activities/events of special significance within an organisation, given streams of low-level information that are difficult to be utilised by humans [4]. Systems for event processing and in part...

What Pharmacometricians (Should) Do

Many people predict that application of modeling and simulation in drug discovery and development will continue to develop and grow rapidly. As a result, the demand for welltrained and experienced quantitative scientists may exceed the supply in the foreseeable future.1 This will be music to the ears of those who are looking to develop their careers in this area, but it may also cause challenge...